KEGG   Bacillus anthracis Ames Ancestor: GBAA_pXO1_0172
Entry
GBAA_pXO1_0172    CDS       T00178                                 
Symbol
lef
Name
(GenBank) anthrax lethal factor endopeptidase
  KO
K08645  anthrax lethal toxin endopeptidase [EC:3.4.24.83]
Organism
bar  Bacillus anthracis Ames Ancestor
Pathway
bar04621  NOD-like receptor signaling pathway
Module
bar_M00859  Bacillus anthracis pathogenicity signature, anthrax toxin
Brite
KEGG Orthology (KO) [BR:bar00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    GBAA_pXO1_0172 (lef)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bar01002]
    GBAA_pXO1_0172 (lef)
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins [BR:bar02042]
    GBAA_pXO1_0172 (lef)
Enzymes [BR:bar01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.83  anthrax lethal factor endopeptidase
     GBAA_pXO1_0172 (lef)
Peptidases and inhibitors [BR:bar01002]
 Metallo peptidases
  Family M34: anthrax lethal factor family
   GBAA_pXO1_0172 (lef)
Bacterial toxins [BR:bar02042]
 Type III toxins: Intracellular toxins
  Metalloprotease
   Anthrax lethal toxin
    GBAA_pXO1_0172 (lef)
SSDB
Motif
Pfam: Anthrax-tox_M ATLF AsiA MTIP_N Slx4
Other DBs
NCBI-ProteinID: AAT28913
UniProt: P15917
Structure
Position
pXO1:complement(149357..151786)
AA seq 809 aa
MNIKKEFIKVISMSCLVTAITLSGPVFIPLVQGAGGHGDVGMHVKEKEKNKDENKRKDEE
RNKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAEKLLEKVPSDVLEMYKAIGGKIYIVDGD
ITKHISLEALSEDKKKIKDIYGKDALLHEHYVYAKEGYEPVLVIQSSEDYVENTEKALNV
YYEIGKILSRDILSKINQPYQKFLDVLNTIKNASDSDGQDLLFTNQLKEHPTDFSVEFLE
QNSNEVQEVFAKAFAYYIEPQHRDVLQLYAPEAFNYMDKFNEQEINLSLEELKDQRMLAR
YEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSS
DFLSTEEKEFLKKLQIDIRDSLSEEEKELLNRIQVDSSNPLSEKEKEFLKKLKLDIQPYD
INQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLT
ATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSP
DTRAGYLENGKLILQRNIGLEIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNIN
QEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWKNNIQSDLIKKVTNYLVDGNG
RFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHE
FGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHST
DHAERLKVQKNAPKTFQFINDQIKFIINS
NT seq 2430 nt   +upstreamnt  +downstreamnt
atgaatataaaaaaagaatttataaaagtaattagtatgtcatgtttagtaacagcaatt
actttgagtggtcccgtctttatcccccttgtacagggggcgggcggtcatggtgatgta
ggtatgcacgtaaaagagaaagagaaaaataaagatgagaataagagaaaagatgaagaa
cgaaataaaacacaggaagagcatttaaaggaaatcatgaaacacattgtaaaaatagaa
gtaaaaggggaggaagctgttaaaaaagaggcagcagaaaagctacttgagaaagtacca
tctgatgttttagagatgtataaagcaattggaggaaagatatatattgtggatggtgat
attacaaaacatatatctttagaagcattatctgaagataagaaaaaaataaaagacatt
tatgggaaagatgctttattacatgaacattatgtatatgcaaaagaaggatatgaaccc
gtacttgtaatccaatcttcggaagattatgtagaaaatactgaaaaggcactgaacgtt
tattatgaaataggtaagatattatcaagggatattttaagtaaaattaatcaaccatat
cagaaatttttagatgtattaaataccattaaaaatgcatctgattcagatggacaagat
cttttatttactaatcagcttaaggaacatcccacagacttttctgtagaattcttggaa
caaaatagcaatgaggtacaagaagtatttgcgaaagcttttgcatattatatcgagcca
cagcatcgtgatgttttacagctttatgcaccggaagcttttaattacatggataaattt
aacgaacaagaaataaatctatccttggaagaacttaaagatcaacggatgctggcaaga
tatgaaaaatgggaaaagataaaacagcactatcaacactggagcgattctttatctgaa
gaaggaagaggacttttaaaaaagctgcagattcctattgagccaaagaaagatgacata
attcattctttatctcaagaagaaaaagagcttctaaaaagaatacaaattgatagtagt
gattttttatctactgaggaaaaagagtttttaaaaaagctacaaattgatattcgtgat
tctttatctgaagaagaaaaagagcttttaaatagaatacaggtggatagtagtaatcct
ttatctgaaaaagaaaaagagtttttaaaaaagctgaaacttgatattcaaccatatgat
attaatcaaaggttgcaagatacaggagggttaattgatagtccgtcaattaatcttgat
gtaagaaagcagtataaaagggatattcaaaatattgatgctttattacatcaatccatt
ggaagtaccttgtacaataaaatttatttgtatgaaaatatgaatatcaataaccttaca
gcaaccctaggtgcggatttagttgattccactgataatactaaaattaatagaggtatt
ttcaatgaattcaaaaaaaatttcaaatatagtatttctagtaactatatgattgttgat
ataaatgaaaggcctgcattagataatgagcgtttgaaatggagaatccaattatcacca
gatactcgagcaggatatttagaaaatggaaagcttatattacaaagaaacatcggtctg
gaaataaaggatgtacaaataattaagcaatccgaaaaagaatatataaggattgatgcg
aaagtagtgccaaagagtaaaatagatacaaaaattcaagaagcacagttaaatataaat
caggaatggaataaagcattagggttaccaaaatatacaaagcttattacattcaacgtg
cataatagatatgcatccaatattgtagaaagtgcttatttaatattgaatgaatggaaa
aataatattcaaagtgatcttataaaaaaggtaacaaattacttagttgatggtaatgga
agatttgtttttaccgatattactctccctaatatagctgaacaatatacacatcaagat
gagatatatgagcaagttcattcaaaagggttatatgttccagaatcccgttctatatta
ctccatggaccttcaaaaggtgtagaattaaggaatgatagtgagggttttatacacgaa
tttggacatgctgtggatgattatgctggatatctattagataagaaccaatctgattta
gttacaaattctaaaaaattcattgatatttttaaggaagaagggagtaatttaacttcg
tatgggagaacaaatgaagcggaattttttgcagaagcctttaggttaatgcattctacg
gaccatgctgaacgtttaaaagttcaaaaaaatgctccgaaaactttccaatttattaac
gatcagattaagttcattattaactcataa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (1)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG ORTHOLOGY (1)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   OC (1)   
   PROTHERM (4)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
3D Structure (32)   
   PDB (32)   
Protein domain (5)   
   Pfam (5)   
All databases (94)   

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